Across TCGA pan-cancer cohorts, CPVL-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CPVL-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CPVL-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CPVL-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and BLCA are the cancer types where CPVL-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CPVL-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	−0.146	<.001	10	view →
KICH	All	All	−0.128	.004	4	view →
BLCA	All	All	+0.080	.049	2	view →
THCA	Female	II,III,IV	−0.112	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CPVL-AS1 RNA expression & survival · all CPVL-AS1 data types