CPTP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CPTP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CPTP data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher CPTP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CPTP expression acts as an unfavorable survival marker.

BLCA, HNSC, and SKCM are the cancer types where CPTP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianAll0.0510.720<.00124view →
HNSCOSMedianII,III,IV0.2060.716.00124view →
SKCMDFSMedianAll0.0150.758<.0019view →
STADOSMedianIII,IV0.5010.633.0125view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration