Across TCGA patient cohorts, CPTP mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPTP-associated genes across cancer lineages are MPP, CD8+ Tcm, and lymphatic Endothelial cells. Each is linked with CPTP in more than 1 cancer types. Because this analysis shows association rather than direction, both CPTP-to-partner and partner-to-CPTP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPTP→partner) and Y-score (partner→CPTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPP →	+0.018	+2.510	.046	.041	3	1
UCEC	CD8+ Tcm →	+0.020	+2.061	.024	.048	3	1
UCEC	lymphatic Endothelial cells →	-0.023	-3.138	.034	.019	3	1
UCEC	pDC →	+0.052	+3.202	.022	.009	3	1
UCEC	Class-switched memory B-cells →	-0.063	-2.584	.019	.011	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

CPTP survival (RNA) · tumor vs normal (RNA) · all CPTP data types