CPT2

Across TCGA cell cohorts, CPT2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPT2-associated genes across cancer lineages are OR6C74, TGM7, and SLCO6A1. Each is linked with CPT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPT2-to-partner and partner-to-CPT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C74 grouped by CPT2-low versus CPT2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT2→partner) and Y-score (partner→CPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR6C74 →	+0.040	+5.357	<.001	.001	3	1
BLOOD_Leukemia	TGM7 →	+0.116	+4.037	<.001	.004	3	1
BLOOD_Leukemia	SLCO6A1 →	+0.360	+4.984	<.001	.002	3	1
LARGE_INTESTINE	GABRG1 →	+0.009	+3.196	.001	.007	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR6C74 by CPT2 expression — CNS

Explore this box plot interactively →