Across TCGA pan-cancer cohorts, CPT1B mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CPT1B data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CPT1B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CPT1B expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC and CCRCC are the cancer types where CPT1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.875	0.328	.018	6	view →
CCRCC	DFS	Quartile	III,IV	0.047	0.714	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CPT1B tumor-vs-normal RNA expression · all CPT1B data types