Across TCGA patient cohorts, CPT1B mutation is significantly associated with the RNA expression of many other genes, with 3,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPT1B-associated genes across cancer lineages are LINC00869, ATP6V1B2, and BBS4. Each is linked with CPT1B in more than 2 cancer types. Because this analysis shows association rather than direction, both CPT1B-to-partner and partner-to-CPT1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT1B→partner) and Y-score (partner→CPT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00869 →	-0.513	-3.552	<.001	.002	3	3
COAD	ATP6V1B2 →	+0.633	+3.321	.001	.009	3	3
COAD	BBS4 →	+0.429	+3.499	.006	.002	3	3
UCEC	MTA2 →	+0.411	+3.502	.001	.002	3	2
UCEC	CHEK1 →	+0.598	+1.786	.002	.008	3	2
UCEC	HIRIP3 →	+0.409	+3.732	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,380 associations by consensus.

Exploration

CPT1B survival (RNA) · tumor vs normal (RNA) · all CPT1B data types