Across TCGA patient cohorts, CPT1B mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPT1B-associated genes across cancer lineages are ATM, MSH2, and ERK2. Each is linked with CPT1B in more than 3 cancer types. Because this analysis shows association rather than direction, both CPT1B-to-partner and partner-to-CPT1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT1B→partner) and Y-score (partner→CPT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.612	-2.321	.001	.006	3	4
UCEC	MSH2 →	-0.300	-2.312	.001	.034	3	3
UCEC	ERK2 →	+0.217	+2.459	.006	.019	3	1
UCEC	MEK1 →	+0.411	+2.321	.006	.006	3	1
UCEC	p62 Lck ligand →	+0.338	+1.807	.012	.027	3	1
UCEC	P-Cadherin →	-0.161	-3.169	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

CPT1B survival (RNA) · tumor vs normal (RNA) · all CPT1B data types