CPT1A

Across TCGA cell cohorts, CPT1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,462 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CPT1A-associated GO terms across cancer lineages are Fatty acid transmembrane transport, Carnitine shuttle, and Eating behavior. Each is linked with CPT1A in more than 12 cancer types. Because this analysis shows association rather than direction, both CPT1A-to-partner and partner-to-CPT1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid transmembrane transport grouped by CPT1A-low versus CPT1A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT1A→partner) and Y-score (partner→CPT1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Fatty acid transmembrane transport →	+0.151	+2.522	.002	<.001	3	13
LUNG_SCLC	Carnitine shuttle →	+0.404	+2.543	.005	<.001	3	12
STOMACH	Eating behavior →	+0.372	+1.947	<.001	.001	3	12
KIDNEY	Positive regulation of fatty acid beta-oxidation →	+0.152	+1.558	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Intracellular lipid transport →	+0.060	+1.730	.004	.001	3	10
BLOOD_Leukemia	Mitochondrial transmembrane transport →	+0.089	+2.070	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,462 associations by consensus.

Fatty acid transmembrane transport by CPT1A expression — LUNG_SCLC

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