CPT1A

Across TCGA cell cohorts, CPT1A mutation is significantly associated with the RNA expression of many other genes, with 418 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPT1A-associated genes across cancer lineages are GGA1, USP14, and MTFMT. Each is linked with CPT1A in more than 1 cancer types. Because this analysis shows association rather than direction, both CPT1A-to-partner and partner-to-CPT1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGA1 grouped by CPT1A-low versus CPT1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT1A→partner) and Y-score (partner→CPT1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GGA1 →	+0.661	+3.364	.002	.002	3	1
LARGE_INTESTINE	USP14 →	+0.780	+3.067	<.001	.009	3	1
LARGE_INTESTINE	MTFMT →	+0.487	+3.169	.009	.009	3	1
LARGE_INTESTINE	GSR →	+0.746	+3.364	.009	.002	3	1
LARGE_INTESTINE	UBXN8 →	+0.849	+3.169	.001	.009	3	1
LARGE_INTESTINE	GYS1 →	+0.821	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

GGA1 by CPT1A expression — LARGE_INTESTINE

Explore this box plot interactively →