CPSF6

Across TCGA patient cohorts, CPSF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,019 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPSF6-associated proteins across cancer lineages are SAE1, GTF3C1, and TRIM28. Each is linked with CPSF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CPSF6-to-partner and partner-to-CPSF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPSF6 versus SAE1 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF6→partner) and Y-score (partner→CPSF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAE1 →	+0.272	+0.572	<.001	<.001	3	6
LSCC	GTF3C1 →	+0.302	+0.503	<.001	<.001	3	6
GBM	TRIM28 →	+0.315	+0.565	<.001	<.001	3	6
GBM	RBM12 →	+0.255	+0.596	<.001	<.001	3	6
GBM	DHX9 →	+0.340	+0.700	<.001	<.001	2	7
HNSC	RPRD2_S928 →	+0.680	+0.734	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,019 associations by consensus.

CPSF6 vs SAE1 — HNSC

Explore this scatter interactively →