CPSF2

Across TCGA cell cohorts, CPSF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,818 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPSF2-associated GO terms across cancer lineages are Heterochromatin organization, Double-strand break repair, and Protein localization to condensed chromosome. Each is linked with CPSF2 in more than 17 cancer types. Because this analysis shows association rather than direction, both CPSF2-to-partner and partner-to-CPSF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by CPSF2-low versus CPSF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF2→partner) and Y-score (partner→CPSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin organization →	+0.071	+0.756	.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.062	+1.034	.005	.004	3	17
LUNG_NSCLC_LUSC	Protein localization to condensed chromosome →	+0.163	+0.758	.009	.006	3	16
BREAST	Regulation of chromosome organization →	+0.073	+0.819	.004	.002	3	16
PANCREAS	Protein localization to chromosome →	+0.106	+0.864	<.001	.002	3	16
OESOPHAGUS	Interstrand cross-link repair →	+0.093	+0.905	.009	.007	1	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,818 associations by consensus.

Heterochromatin organization by CPSF2 expression — OVARY

Explore this box plot interactively →