CPSF1

Across TCGA patient cohorts, CPSF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,761 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPSF1-associated proteins across cancer lineages are ATAD2, SCRIB, and SF3B3. Each is linked with CPSF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPSF1-to-partner and partner-to-CPSF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPSF1 versus ATAD2 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF1→partner) and Y-score (partner→CPSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATAD2 →	+0.655	+0.765	<.001	.002	3	5
BRCA	SCRIB →	+0.415	+0.883	<.001	<.001	3	5
LSCC	SF3B3 →	+0.191	+0.416	<.001	.002	3	4
LSCC	SMC3 →	+0.276	+0.517	.001	<.001	2	5
BRCA	TAF2 →	+0.301	+0.834	<.001	.001	3	4
BRCA	HSF1 →	+0.526	+1.249	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,761 associations by consensus.

CPSF1 vs ATAD2 — BRCA

Explore this scatter interactively →