CPS1

Across TCGA patient cohorts, CPS1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,269 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CPS1-associated genes across cancer lineages are CPS1-IT1, KIRREL1, and KIRREL1-IT1. Each is linked with CPS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPS1-to-partner and partner-to-CPS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPS1 versus CPS1-IT1 in LUAD, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPS1→partner) and Y-score (partner→CPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CPS1-IT1 →	+1.170	+1.837	<.001	<.001	3	5
LUAD	KIRREL1 →	-0.670	-1.949	<.001	<.001	3	3
LUAD	KIRREL1-IT1 →	-0.836	-2.025	<.001	<.001	3	3
LUAD	DNAJC12 →	+1.272	+1.498	<.001	<.001	3	3
OV	HELLS →	-0.637	-0.751	.003	.004	3	2
LUAD	LSS →	-0.440	-1.741	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,269 associations by consensus.

CPS1 vs CPS1-IT1 — LUAD

Explore this scatter interactively →