CPPED1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CPPED1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CPPED1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CPPED1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CPPED1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, GBM, and COAD are the cancer types where CPPED1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSTertileIII,IV1.0000.797.02111view →
GBMOSQuartileAll0.4280.785.0018view →
COADDFSMedianIII,IV0.8971.000.0446view →
LUADOSQuartileII,III,IV0.9360.498.0306view →
LSCCOSMedianII,III,IV0.8730.700.0351view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CPPED1–CCRCC (OS)

Kaplan–Meier survival curve for CPPED1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration