CPP

Across TCGA pan-cancer cohorts, CPP RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CPP data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher CPP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CPP expression acts as an unfavorable survival marker, although some lineages such as ACC and UCS show a favorable association.

KICH, LGG, and ESCA are the cancer types where CPP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.497	0.939	.001	60	view →
LGG	DFS	Median	All	0.667	0.803	<.001	50	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	40	view →
ACC	DFS	Tertile	All	0.920	0.440	.003	27	view →
KIRP	DFS	Median	III,IV	0.096	0.567	.001	26	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LUAD	OS	Median	All	0.777	0.845	.004	24	view →
UVM	DFS	Median	All	0.333	0.669	.004	22	view →
STAD	DFS	Tertile	All	0.579	0.716	.007	15	view →
DLBC	DFS	Median	All	0.629	1.000	.017	13	view →
GBM	DFS	Quartile	All	0.174	0.409	.009	12	view →
LUSC	DFS	Quartile	All	0.326	0.484	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CPP–KICH (DFS)

Open the KICH breakdown →