CPNE8

Across TCGA patient cohorts, CPNE8 protein abundance is significantly associated with the RNA expression of many other genes, with 9,006 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CPNE8-associated genes across cancer lineages are CPNE8-AS1, TLR2, and TMBIM1. Each is linked with CPNE8 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPNE8-to-partner and partner-to-CPNE8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPNE8 versus CPNE8-AS1 in GBM, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE8→partner) and Y-score (partner→CPNE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CPNE8-AS1 →	+1.123	+0.658	<.001	<.001	3	6
UCEC	TLR2 →	+0.905	+0.429	<.001	.001	3	5
BRCA	TMBIM1 →	+0.619	+0.433	<.001	<.001	3	5
HNSC	CA2 →	+1.762	+0.231	<.001	.002	3	4
BRCA	EDN2 →	+1.230	+0.310	.004	.006	3	4
BRCA	CARD6 →	+0.743	+0.444	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,006 associations by consensus.

CPNE8 vs CPNE8-AS1 — GBM

Explore this scatter interactively →