CPNE5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CPNE5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,152 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CPNE5-associated GO terms across cancer lineages are Negative regulation of respiratory burst involved in inflammatory response, Negative regulation of respiratory burst, and Intrinsic apoptotic signaling pathway. Each is linked with CPNE5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CPNE5-to-partner and partner-to-CPNE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of respiratory burst involved in inflammatory response grouped by CPNE5-low versus CPNE5-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE5→partner) and Y-score (partner→CPNE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNegative regulation of respiratory burst involved in inflammatory response →+0.107+1.792.001.00337
BLOOD_LymphomaNegative regulation of respiratory burst →+0.107+1.792.001.00337
LARGE_INTESTINEIntrinsic apoptotic signaling pathway →+0.029+0.185.003.00536
PANCREASRegulation of protein localization to nucleus →+0.069+0.263<.001<.00127
LUNG_NSCLC_LUADRegulation of viral life cycle →+0.056+0.354<.001.00136
LUNG_NSCLC_LUADNegative regulation of protein transport →+0.038+0.371<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,152 associations by consensus.

Negative regulation of respiratory burst involved in inflammatory response by CPNE5 expression — BLOOD_Lymphoma

Box plot of Negative regulation of respiratory burst involved in inflammatory response in CPNE5-low vs CPNE5-high samples in BLOOD_Lymphoma.

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Exploration