CPNE5

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CPNE5 mutation is significantly associated with the drug of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPNE5-associated genes across cancer lineages are 50869, 630600, and Schweinfurthin A. Each is linked with CPNE5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE5-to-partner and partner-to-CPNE5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by CPNE5-low versus CPNE5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE5→partner) and Y-score (partner→CPNE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINE50869 →+0.469+2.649.026.04631
LARGE_INTESTINE630600 →+0.795+2.649.009.04631
LARGE_INTESTINESchweinfurthin A →+0.568+2.649.031.04631
LARGE_INTESTINEPRT062607 →+0.732+2.769.003.04021
LARGE_INTESTINEGSK626616AC →+0.344+2.777.031.03821
LARGE_INTESTINEIspinesib Mesylate →+0.706+2.652.030.04521
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

50869 by CPNE5 expression — LARGE_INTESTINE

Box plot of 50869 in CPNE5-low vs CPNE5-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration