Across TCGA patient cohorts, CPNE4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,420 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPNE4-associated genes across cancer lineages are IGDCC4, TNFRSF19, and ADAMTS18. Each is linked with CPNE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE4-to-partner and partner-to-CPNE4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE4→partner) and Y-score (partner→CPNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IGDCC4 →	+0.659	+0.565	<.001	<.001	3	2
BRCA	TNFRSF19 →	+1.605	+1.133	.005	<.001	3	2
GBM	ADAMTS18 →	+1.034	+0.614	<.001	<.001	3	2
BRCA	ANK2 →	+0.685	+0.725	.001	.001	3	2
BRCA	TMEM178A →	+0.811	+0.964	.002	<.001	3	2
BRCA	SPARCL1 →	+1.421	+1.046	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,420 associations by consensus.

Exploration

CPNE4 survival (RNA) · tumor vs normal (RNA) · all CPNE4 data types