Across TCGA patient cohorts, CPNE4 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,408 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPNE4-associated proteins across cancer lineages are PI4K2B, EP400_T974, and NFATC4. Each is linked with CPNE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE4-to-partner and partner-to-CPNE4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE4→partner) and Y-score (partner→CPNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PI4K2B →	-0.519	-1.246	<.001	<.001	3	2
BRCA	EP400_T974 →	-1.108	-1.133	<.001	.001	3	2
BRCA	NFATC4 →	+0.445	+0.995	.002	<.001	3	2
BRCA	APOA2 →	+0.968	+0.902	.001	.004	3	1
BRCA	APOC4 →	+1.010	+1.014	<.001	<.001	3	1
BRCA	APOL1 →	+0.794	+0.923	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,408 associations by consensus.

Exploration

CPNE4 survival (RNA) · tumor vs normal (RNA) · all CPNE4 data types