Across TCGA patient cohorts, CPNE4 mutation is significantly associated with the RNA expression of many other genes, with 3,301 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPNE4-associated genes across cancer lineages are GET3, SRFBP1, and GPATCH11. Each is linked with CPNE4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPNE4-to-partner and partner-to-CPNE4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE4→partner) and Y-score (partner→CPNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GET3 →	+0.258	+2.273	.002	.004	3	4
UCEC	SRFBP1 →	+0.418	+1.872	.008	.004	3	3
UCEC	GPATCH11 →	+0.423	+2.502	<.001	<.001	3	3
UCEC	C12orf43 →	+0.262	+2.180	.001	<.001	3	3
UCEC	ABCE1 →	+0.424	+1.880	.009	.004	3	3
COAD	WDR41 →	+0.546	+3.210	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,301 associations by consensus.

Exploration

CPNE4 survival (RNA) · tumor vs normal (RNA) · all CPNE4 data types