Across TCGA patient cohorts, CPNE4 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPNE4-associated genes across cancer lineages are eIF4E, Lck, and ATM. Each is linked with CPNE4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPNE4-to-partner and partner-to-CPNE4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE4→partner) and Y-score (partner→CPNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.178	+3.335	.011	.005	3	3
UCEC	Lck →	+0.200	+1.807	.002	.025	3	3
UCEC	ATM →	-0.660	-2.201	<.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.903	+3.999	<.001	<.001	3	3
UCEC	GAPDH →	+0.385	+1.584	.032	.034	3	2
UCEC	PCNA →	+0.237	+2.906	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

CPNE4 survival (RNA) · tumor vs normal (RNA) · all CPNE4 data types