Across TCGA cell cohorts, CPNE4 mutation is significantly associated with the RNA expression of many other genes, with 176 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPNE4-associated genes across cancer lineages are MROH5, TEX53, and OR4X2. Each is linked with CPNE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPNE4-to-partner and partner-to-CPNE4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE4→partner) and Y-score (partner→CPNE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MROH5 →	+0.021	+4.930	<.001	.008	3	2
LARGE_INTESTINE	TEX53 →	+0.052	+2.421	.004	.002	3	2
SOFT_TISSUE	OR4X2 →	+0.018	+5.369	.001	.004	3	1
SOFT_TISSUE	MRGPRG →	+0.333	+4.930	<.001	.008	3	1
SOFT_TISSUE	LCE6A →	+0.040	+5.977	<.001	.001	3	1
SKIN	TPPP2 →	+0.085	+5.217	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 176 associations by consensus.

Exploration

CPNE4 survival (RNA) · tumor vs normal (RNA) · all CPNE4 data types