CPNE2

Across TCGA cell cohorts, CPNE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,130 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPNE2-associated GO terms across cancer lineages are Protein depolymerization, Actin filament depolymerization, and Regulation of G1/S transition of mitotic cell cycle. Each is linked with CPNE2 in more than 14 cancer types. Because this analysis shows association rather than direction, both CPNE2-to-partner and partner-to-CPNE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by CPNE2-low versus CPNE2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE2→partner) and Y-score (partner→CPNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein depolymerization →	+0.114	+1.380	<.001	.002	3	15
URINARY_TRACT	Actin filament depolymerization →	+0.219	+1.531	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of G1/S transition of mitotic cell cycle →	+0.063	+1.008	<.001	.001	2	12
BREAST	Protein-containing complex disassembly →	+0.061	+1.156	<.001	.007	2	12
URINARY_TRACT	Positive regulation of supramolecular fiber organization →	+0.083	+1.160	.001	.006	3	11
BREAST	Regulation of cell cycle G1/S phase transition →	+0.064	+1.425	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,130 associations by consensus.

Protein depolymerization by CPNE2 expression — BONE

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