Across TCGA patient cohorts, CPNE1 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPNE1-associated genes across cancer lineages are ATM, ERK2, and C-Raf. Each is linked with CPNE1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPNE1-to-partner and partner-to-CPNE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE1→partner) and Y-score (partner→CPNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.752	-3.584	<.001	.002	3	4
UCEC	ERK2 →	+0.238	+1.906	.002	.016	3	2
UCEC	C-Raf →	+0.129	+2.115	.025	.017	3	2
UCEC	EGFR_pY1068 →	-0.289	-1.700	.004	.042	3	1
UCEC	eIF4E →	+0.203	+3.459	.016	.005	2	2
UCEC	FoxM1 →	+0.221	+2.415	.033	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

CPNE1 survival (RNA) · tumor vs normal (RNA) · all CPNE1 data types