Across TCGA cell cohorts, CPNE1 mutation is significantly associated with the mutation status of many other genes, with 4,784 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPNE1-associated genes across cancer lineages are CABIN1, KDM3B, and PRPF8. Each is linked with CPNE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPNE1-to-partner and partner-to-CPNE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPNE1→partner) and Y-score (partner→CPNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CABIN1 →	+4.562	+5.217	<.001	<.001	1	5
BREAST	KDM3B →	+4.297	+4.857	.009	.009	1	5
BREAST	PRPF8 →	+4.297	+4.857	.009	.009	1	5
OVARY	RTN4 →	+4.562	+5.217	<.001	<.001	1	5
LARGE_INTESTINE	NCAPD3 →	+2.000	+2.662	.008	.008	1	5
BLOOD_Leukemia	LRRK2 →	+2.662	+3.169	.001	.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Exploration

CPNE1 survival (RNA) · tumor vs normal (RNA) · all CPNE1 data types