CPN1

Across TCGA patient cohorts, CPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,506 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CPN1-associated GO terms across cancer lineages are Nucleoside bisphosphate metabolic process, Water-soluble vitamin biosynthetic process, and Polyamine biosynthetic process. Each is linked with CPN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CPN1-to-partner and partner-to-CPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside bisphosphate metabolic process grouped by CPN1-low versus CPN1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN1→partner) and Y-score (partner→CPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside bisphosphate metabolic process →	+0.049	+0.528	<.001	<.001	3	13
STAD	Water-soluble vitamin biosynthetic process →	+0.052	+0.543	<.001	<.001	3	12
STAD	Polyamine biosynthetic process →	+0.073	+0.554	<.001	<.001	3	11
STAD	Thioester metabolic process →	+0.048	+0.437	<.001	<.001	3	10
STAD	Aerobic respiration →	+0.068	+0.384	<.001	<.001	3	10
STAD	[2Fe-2S] cluster assembly →	+0.044	+0.329	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,506 associations by consensus.

Nucleoside bisphosphate metabolic process by CPN1 expression — STAD

Explore this box plot interactively →