CPN1

Across TCGA patient cohorts, CPN1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,479 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPN1-associated genes across cancer lineages are MMP19, SLC2A3, and IL6. Each is linked with CPN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CPN1-to-partner and partner-to-CPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPN1 versus MMP19 in GBM, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN1→partner) and Y-score (partner→CPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP19 →	+1.188	+0.520	<.001	<.001	3	8
LUAD	SLC2A3 →	+1.455	+0.619	<.001	<.001	3	8
GBM	IL6 →	+1.919	+0.909	<.001	<.001	3	8
OV	SERPINE1 →	+1.349	+0.385	<.001	.001	3	7
OV	DIPK2B →	+0.684	+0.676	.002	<.001	3	7
LSCC	ITGA5 →	+0.847	+0.436	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,479 associations by consensus.

CPN1 vs MMP19 — GBM

Explore this scatter interactively →