CPN1

Across TCGA cell cohorts, CPN1 mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPN1-associated genes across cancer lineages are RBP3, ACER1, and PRR30. Each is linked with CPN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPN1-to-partner and partner-to-CPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBP3 grouped by CPN1-low versus CPN1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPN1→partner) and Y-score (partner→CPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	RBP3 →	+0.006	+4.807	<.001	.006	3	2
LARGE_INTESTINE	ACER1 →	+0.098	+3.823	.001	.006	3	2
BLOOD_Leukemia	PRR30 →	+0.012	+3.362	<.001	.001	3	2
BLOOD_Myeloma	PRORY →	+1.180	+4.807	<.001	.006	3	1
BLOOD_Myeloma	DAZ3 →	+1.563	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	GPR119 →	+0.022	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

RBP3 by CPN1 expression — BLOOD_Myeloma

Explore this box plot interactively →