Across TCGA patient cohorts, CPLX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,798 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CPLX3-associated GO terms across cancer lineages are Mitochondrial gene expression, Aerobic respiration, and Membrane fusion. Each is linked with CPLX3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPLX3-to-partner and partner-to-CPLX3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX3→partner) and Y-score (partner→CPLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.162	+0.002	<.001	.003	3	4
STAD	Aerobic respiration →	+0.178	+0.003	<.001	.004	3	4
STAD	Membrane fusion →	+0.115	+0.003	<.001	.001	3	3
STAD	Protein localization to mitochondrion →	+0.146	+0.002	<.001	.002	3	3
STAD	Organelle membrane fusion →	+0.127	+0.004	<.001	.002	3	3
STAD	Regulation of vesicle size →	+0.125	+0.003	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,798 associations by consensus.

Exploration

CPLX3 survival (RNA) · tumor vs normal (RNA) · all CPLX3 data types