Across TCGA patient cohorts, CPLX3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,342 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLX3-associated genes across cancer lineages are PRODH, SOX10, and SLC16A8. Each is linked with CPLX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPLX3-to-partner and partner-to-CPLX3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX3→partner) and Y-score (partner→CPLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.603	+0.729	.008	.001	3	1
GBM	SOX10 →	+1.460	+0.669	<.001	.003	3	1
GBM	SLC16A8 →	+0.546	+0.711	<.001	.001	3	1
GBM	SEPTIN3 →	+1.268	+1.029	<.001	<.001	3	1
GBM	XBP1 →	-0.499	-1.023	.001	.003	3	1
GBM	SUN2 →	+0.414	+0.768	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,342 associations by consensus.

Exploration

CPLX3 survival (RNA) · tumor vs normal (RNA) · all CPLX3 data types