Across TCGA patient cohorts, CPLX3 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,990 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLX3-associated proteins across cancer lineages are ACIN1_S384, ARPC5L_S64, and ACIN1_S410. Each is linked with CPLX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPLX3-to-partner and partner-to-CPLX3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX3→partner) and Y-score (partner→CPLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACIN1_S384 →	-0.367	-0.966	<.001	<.001	3	1
GBM	ARPC5L_S64 →	+0.500	+1.023	<.001	<.001	3	1
GBM	ACIN1_S410 →	-0.302	-0.901	.001	.002	3	1
GBM	ARPP19 →	+0.271	+0.730	<.001	.003	3	1
GBM	ARPP21 →	+0.772	+1.069	<.001	<.001	3	1
GBM	ARPP21_S138 →	+1.074	+1.116	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,990 associations by consensus.

Exploration

CPLX3 survival (RNA) · tumor vs normal (RNA) · all CPLX3 data types