Across TCGA patient cohorts, CPLX3 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPLX3-associated genes across cancer lineages are RNU1-68P, RNU6-907P, and RN7SKP83. Each is linked with CPLX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPLX3-to-partner and partner-to-CPLX3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX3→partner) and Y-score (partner→CPLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-68P →	+0.111	+4.069	<.001	.008	3	2
UCEC	RNU6-907P →	+0.366	+3.759	.001	<.001	3	2
UCEC	RN7SKP83 →	+0.386	+4.211	<.001	<.001	3	2
UCEC	RNA5SP414 →	+0.668	+3.577	<.001	<.001	3	1
COAD	RNA5SP453 →	+0.529	+5.693	<.001	.003	3	1
COAD	RPSAP65 →	+0.132	+5.435	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

Exploration

CPLX3 survival (RNA) · tumor vs normal (RNA) · all CPLX3 data types