CPLX2

Across TCGA patient cohorts, CPLX2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,154 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLX2-associated genes across cancer lineages are PTPRN2, RUNDC3A, and SYT5. Each is linked with CPLX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CPLX2-to-partner and partner-to-CPLX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPLX2 versus PTPRN2 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX2→partner) and Y-score (partner→CPLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPRN2 →	+2.904	+2.915	<.001	<.001	3	4
BRCA	RUNDC3A →	+2.935	+2.645	<.001	<.001	3	4
OV	SYT5 →	+1.160	+1.388	.003	<.001	3	3
GBM	CPEB1 →	+0.583	+1.162	<.001	<.001	3	3
GBM	HNRNPA1P42 →	+0.481	+0.810	<.001	<.001	3	3
BRCA	SYP →	+2.635	+2.962	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,154 associations by consensus.

CPLX2 vs PTPRN2 — BRCA

Explore this scatter interactively →