CPLX2

Across TCGA patient cohorts, CPLX2 mutation is significantly associated with the RNA expression of many other genes, with 2,748 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPLX2-associated genes across cancer lineages are LINC01997, MIR4478, and ACSL6-AS1. Each is linked with CPLX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPLX2-to-partner and partner-to-CPLX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01997 grouped by CPLX2-low versus CPLX2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX2→partner) and Y-score (partner→CPLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01997 →	+1.126	+3.612	<.001	.006	3	2
CESC	MIR4478 →	+0.968	+3.411	.001	.009	3	2
CESC	ACSL6-AS1 →	+0.115	+4.569	<.001	.005	3	2
UCEC	MIR6859-4 →	+0.429	+2.055	<.001	.002	3	2
UCEC	YJU2 →	+0.436	+2.662	<.001	<.001	3	2
UCEC	RNA5SP410 →	+0.596	+2.258	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,748 associations by consensus.

LINC01997 by CPLX2 expression — CESC

Explore this box plot interactively →