CPLX2

Across TCGA cell cohorts, CPLX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,353 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CPLX2-associated GO terms across cancer lineages are mRNA cis splicing, via spliceosome, Cytoplasmic translational initiation, and Epigenetic regulation of gene expression. Each is linked with CPLX2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CPLX2-to-partner and partner-to-CPLX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA cis splicing, via spliceosome grouped by CPLX2-low versus CPLX2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX2→partner) and Y-score (partner→CPLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	mRNA cis splicing, via spliceosome →	+0.070	+0.089	<.001	.001	3	6
PANCREAS	Cytoplasmic translational initiation →	+0.076	+0.059	<.001	.007	2	7
BLOOD_Lymphoma	Epigenetic regulation of gene expression →	+0.037	+0.052	.003	.003	2	6
LUNG_SCLC	Collagen catabolic process →	-0.193	-4.094	.009	<.001	3	5
LUNG_SCLC	Establishment of vesicle localization →	+0.064	+3.592	<.001	<.001	3	5
BLOOD_Myeloma	Transcription initiation-coupled chromatin remodeling →	+0.050	+0.052	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,353 associations by consensus.

mRNA cis splicing, via spliceosome by CPLX2 expression — BLOOD_Lymphoma

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