CPLX1

Across TCGA patient cohorts, CPLX1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLX1-associated genes across cancer lineages are MMP26, FAM71E1, and SYN3-AS1. Each is linked with CPLX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPLX1-to-partner and partner-to-CPLX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPLX1 versus MMP26 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX1→partner) and Y-score (partner→CPLX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MMP26 →	+0.307	+1.217	.008	<.001	3	3
UCEC	FAM71E1 →	+0.925	+0.739	.009	.003	3	2
GBM	SYN3-AS1 →	+1.182	+0.968	<.001	<.001	3	2
UCEC	SRP68P3 →	+1.206	+0.647	.001	.002	3	2
UCEC	EPHA6 →	+1.277	+0.990	.008	.003	3	2
LSCC	PNPLA5 →	+1.056	+1.310	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,430 associations by consensus.

CPLX1 vs MMP26 — BRCA

Explore this scatter interactively →