CPLX1

Across TCGA patient cohorts, CPLX1 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CPLX1-associated proteins across cancer lineages are BEGAIN_S455, ADO, and RBM47. Each is linked with CPLX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPLX1-to-partner and partner-to-CPLX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPLX1 versus BEGAIN_S455 in BRCA, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLX1→partner) and Y-score (partner→CPLX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BEGAIN_S455 →	+1.832	+2.247	<.001	.001	3	3
UCEC	ADO →	+0.507	+1.171	<.001	<.001	3	3
GBM	RBM47 →	-0.796	-1.093	<.001	<.001	3	3
LSCC	HCK →	-0.746	-1.481	.002	.001	3	3
BRCA	APEH_S187 →	+0.426	+0.828	<.001	.003	3	2
BRCA	BRD9_S566 →	+1.148	+1.294	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,283 associations by consensus.

CPLX1 vs BEGAIN_S455 — BRCA

Explore this scatter interactively →