CPLANE2

Across TCGA patient cohorts, CPLANE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,455 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CPLANE2-associated proteins across cancer lineages are WDR54, OSCP1, and ARHGEF16. Each is linked with CPLANE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPLANE2-to-partner and partner-to-CPLANE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPLANE2 versus WDR54 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLANE2→partner) and Y-score (partner→CPLANE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR54 →	+0.523	+1.170	<.001	<.001	3	6
GBM	OSCP1 →	+0.548	+0.571	<.001	<.001	3	6
LSCC	ARHGEF16 →	+0.523	+0.531	<.001	<.001	3	4
GBM	MTHFD2 →	-0.483	-0.515	.001	<.001	3	4
BRCA	NFIA →	+0.404	+0.665	.001	<.001	3	4
COAD	NUDC →	+0.433	+0.513	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,455 associations by consensus.

CPLANE2 vs WDR54 — UCEC

Explore this scatter interactively →