Across TCGA cell cohorts, CPLANE1 mutation is significantly associated with the RNA expression of many other genes, with 2,300 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPLANE1-associated genes across cancer lineages are CEP83, PIH1D1, and PIAS4. Each is linked with CPLANE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPLANE1-to-partner and partner-to-CPLANE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPLANE1→partner) and Y-score (partner→CPLANE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CEP83 →	+0.484	+2.222	.003	.001	3	3
LARGE_INTESTINE	PIH1D1 →	+0.438	+1.808	.001	.001	3	3
LARGE_INTESTINE	PIAS4 →	+0.613	+1.808	.001	.001	3	3
LARGE_INTESTINE	TRIM37 →	+0.524	+1.458	.001	.009	3	3
LARGE_INTESTINE	YWHAE →	+0.514	+2.212	.001	<.001	3	3
LARGE_INTESTINE	CEP70 →	+0.788	+1.808	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,300 associations by consensus.

Exploration

CPLANE1 survival (RNA) · tumor vs normal (RNA) · all CPLANE1 data types