CPED1

Across TCGA patient cohorts, CPED1 mutation is significantly associated with the RNA expression of many other genes, with 5,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPED1-associated genes across cancer lineages are MRPS35, CDCA2, and FUZ. Each is linked with CPED1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPED1-to-partner and partner-to-CPED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS35 grouped by CPED1-low versus CPED1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPED1→partner) and Y-score (partner→CPED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPS35 →	+0.365	+1.385	.001	.009	3	5
COAD	CDCA2 →	+0.876	+3.713	<.001	<.001	3	4
UCEC	FUZ →	-0.556	-1.574	<.001	<.001	3	4
UCEC	EIF3J →	+0.499	+3.403	<.001	<.001	3	4
UCEC	OIP5 →	+0.799	+2.191	<.001	<.001	3	4
LUSC	NSD2 →	+0.606	+3.333	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,745 associations by consensus.

MRPS35 by CPED1 expression — UCEC

Explore this box plot interactively →