CPED1

Across TCGA patient cohorts, CPED1 mutation is significantly associated with the total protein of many other genes, with 74 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPED1-associated genes across cancer lineages are MIG-6, Cyclin-B1, and FASN. Each is linked with CPED1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPED1-to-partner and partner-to-CPED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by CPED1-low versus CPED1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPED1→partner) and Y-score (partner→CPED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIG-6 →	+0.274	+3.016	.002	.018	3	5
UCEC	Cyclin-B1 →	+0.631	+4.087	<.001	<.001	3	3
UCEC	FASN →	+0.303	+1.295	.008	.010	3	3
COAD	PCNA →	+0.256	+2.467	.017	.011	3	3
COAD	PDCD4 →	-0.572	-2.321	.001	.033	3	3
UCEC	STAT3_pY705 →	-0.301	-1.222	<.001	.029	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

MIG-6 by CPED1 expression — LUAD

Explore this box plot interactively →