CPED1

Across TCGA cell cohorts, CPED1 mutation is significantly associated with the RNA expression of many other genes, with 727 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPED1-associated genes across cancer lineages are CENPVL3, CYP4Z1, and CCT8L2. Each is linked with CPED1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPED1-to-partner and partner-to-CPED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPVL3 grouped by CPED1-low versus CPED1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPED1→partner) and Y-score (partner→CPED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CENPVL3 →	+0.812	+3.629	<.001	.003	3	2
LARGE_INTESTINE	CYP4Z1 →	+0.157	+2.431	.008	.005	3	2
BLOOD_Leukemia	CCT8L2 →	+0.015	+3.874	<.001	.005	3	2
OVARY	MTNR1A →	+0.231	+3.199	<.001	.008	3	2
LARGE_INTESTINE	DESI1 →	+0.464	+3.169	.003	.009	3	2
LARGE_INTESTINE	INTS10 →	+0.622	+3.628	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

CENPVL3 by CPED1 expression — LUNG_SCLC

Explore this box plot interactively →