CPEB2

Across TCGA patient cohorts, CPEB2 mutation is significantly associated with the RNA expression of many other genes, with 4,200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPEB2-associated genes across cancer lineages are RN7SKP231, CCND3P2, and RNA5SP418. Each is linked with CPEB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPEB2-to-partner and partner-to-CPEB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP231 grouped by CPEB2-low versus CPEB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPEB2→partner) and Y-score (partner→CPEB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP231 →	+0.106	+5.900	<.001	<.001	3	2
LUAD	CCND3P2 →	+0.129	+7.599	<.001	<.001	3	2
UCEC	RNA5SP418 →	+0.552	+1.541	<.001	.005	3	2
UCEC	RNA5SP228 →	+0.074	+2.830	<.001	.007	3	2
UCEC	RNA5SP422 →	+0.584	+1.545	<.001	.003	3	2
BRCA	RNU6-210P →	+0.295	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,200 associations by consensus.

RN7SKP231 by CPEB2 expression — SKCM

Explore this box plot interactively →