CPB2-AS1

Across TCGA pan-cancer cohorts, CPB2-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CPB2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CPB2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CPB2-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and LUSC are the cancer types where CPB2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CPB2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−0.280	<.001	10	view →
KIRC	Female	II,III,IV	−0.193	<.001	10	view →
LUSC	All	II,III,IV	−0.165	<.001	8	view →
THCA	Female	All	−0.207	<.001	7	view →
KIRP	Male	III,IV	−0.188	<.001	6	view →
LUAD	Female	II,III,IV	−0.195	<.001	5	view →
BRCA	All	All	−0.107	.002	4	view →
LIHC	Male	All	+0.196	.012	3	view →
BLCA	Female	IV	−0.066	.007	3	view →
CHOL	Female	All	−0.503	.026	2	view →
BRCA	All	IV	+0.245	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

CPB2-AS1–KICH

Open the KICH breakdown →