CPB1

Across TCGA patient cohorts, CPB1 mutation is significantly associated with the RNA expression of many other genes, with 2,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPB1-associated genes across cancer lineages are RNA5SP213, MIR8053, and CASTOR2. Each is linked with CPB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CPB1-to-partner and partner-to-CPB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP213 grouped by CPB1-low versus CPB1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPB1→partner) and Y-score (partner→CPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP213 →	+0.248	+3.343	.004	.006	3	3
COAD	MIR8053 →	+0.360	+4.399	<.001	.006	3	2
UCEC	CASTOR2 →	+0.635	+1.769	.001	.004	3	2
UCEC	TUBGCP5 →	+0.391	+3.010	.002	<.001	3	2
UCEC	TNKS1BP1 →	+0.383	+3.343	.005	.005	3	2
UCEC	INCENP →	+0.585	+3.616	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,093 associations by consensus.

RNA5SP213 by CPB1 expression — LUAD

Explore this box plot interactively →