CPA5

Across TCGA patient cohorts, CPA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CPA5-associated GO terms across cancer lineages are Positive thymic T cell selection, Positive regulation of B cell differentiation, and T cell homeostasis. Each is linked with CPA5 in more than 19 cancer types. Because this analysis shows association rather than direction, both CPA5-to-partner and partner-to-CPA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive thymic T cell selection grouped by CPA5-low versus CPA5-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA5→partner) and Y-score (partner→CPA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Positive thymic T cell selection →	+0.107	+0.344	<.001	<.001	3	20
SKCM	Positive regulation of B cell differentiation →	+0.092	+0.328	<.001	<.001	3	20
STAD	T cell homeostasis →	+0.084	+0.292	<.001	<.001	3	19
SKCM	Regulation of lymphocyte differentiation →	+0.048	+0.377	<.001	<.001	3	19
SKCM	Regulation of alpha-beta T cell activation →	+0.054	+0.337	<.001	<.001	3	19
SKCM	Positive regulation of alpha-beta T cell activation →	+0.059	+0.321	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

Positive thymic T cell selection by CPA5 expression — SKCM

Explore this box plot interactively →