CPA5

Across TCGA cell cohorts, CPA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,681 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPA5-associated GO terms across cancer lineages are Aorta smooth muscle tissue morphogenesis, Regulation of cytokine-mediated signaling pathway, and Regulation of response to cytokine stimulus. Each is linked with CPA5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CPA5-to-partner and partner-to-CPA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aorta smooth muscle tissue morphogenesis grouped by CPA5-low versus CPA5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA5→partner) and Y-score (partner→CPA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Aorta smooth muscle tissue morphogenesis →	+1.444	+0.204	<.001	.008	3	7
PANCREAS	Regulation of cytokine-mediated signaling pathway →	+0.044	+0.207	.001	.006	2	7
KIDNEY	Regulation of response to cytokine stimulus →	+0.059	+0.255	.002	.007	3	6
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.210	+0.542	<.001	.003	3	6
LARGE_INTESTINE	Spliceosomal tri-snRNP complex assembly →	+0.044	+0.171	.004	.004	3	6
BONE	Regulation of mitochondrial membrane potential →	+0.094	+0.517	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,681 associations by consensus.

Aorta smooth muscle tissue morphogenesis by CPA5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →