CPA5

Across TCGA cell cohorts, CPA5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CPA5-associated genes across cancer lineages are FAM9A, SKOR2, and CXorf51A. Each is linked with CPA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPA5-to-partner and partner-to-CPA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM9A grouped by CPA5-low versus CPA5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA5→partner) and Y-score (partner→CPA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FAM9A →	+0.607	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	SKOR2 →	+0.014	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.061	+4.472	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM9A by CPA5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →