CPA4

Across TCGA cell cohorts, CPA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,348 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPA4-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Substrate adhesion-dependent cell spreading, and Pyrimidine-containing compound transmembrane transport. Each is linked with CPA4 in more than 13 cancer types. Because this analysis shows association rather than direction, both CPA4-to-partner and partner-to-CPA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to mitochondrion grouped by CPA4-low versus CPA4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA4→partner) and Y-score (partner→CPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein localization to mitochondrion →	+0.119	+3.001	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Substrate adhesion-dependent cell spreading →	+0.195	+4.022	.001	.002	3	14
LIVER	Pyrimidine-containing compound transmembrane transport →	-0.190	-3.953	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.127	+3.881	<.001	<.001	3	14
BONE	Positive regulation of plasma membrane repair →	+0.373	+6.029	<.001	<.001	3	14
BONE	Dentinogenesis →	+2.237	+4.281	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,348 associations by consensus.

Regulation of protein localization to mitochondrion by CPA4 expression — STOMACH

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